top of page
VitriBiome company logo

STEP 1

Biological Input

Assess the target material, activity, and stability challenge.

The Science That Makes Biologics Shelf-Stable

Our proprietary stabilization platform combines proprietary formulations with specialized drying protocols to immobilize sensitive biological materials within a protective vitrified matrix — helping preserve activity, improve shelf life, and enable ambient-stable product formats.

STEP 2

Stabilization System

Apply proprietary chemistry tailored to the material.

STEP 3

Specialized Drying

Dry under conditions designed to minimize biological stress.

STEP 4

Protective Vitrified Matrix

Immobilization within a protective glass-like state

STEP 5

Commercial Product Formats

Commercial ambient-stable biological products

The Four Pillars of VitriStableâ„¢ Technology

Proprietary Formulation Science

Proprietary stabilization formulations designed to protect sensitive biological materials during dehydration, storage, and distribution.

Optimized Drying Protocols

Controlled drying protocols tailored to the material’s stability profile, balancing water removal with preservation of viability, activity, and performance.

Conventional Equipment Compatibility

Designed to work within existing production environments and conventional lyophilization infrastructure without requiring specialized new equipment.

Protected IP Portfolio

A proprietary formulation-and-process platform supported by patent protection, know-how, and application-specific optimization.

The VitriStableâ„¢ Development Process

01

02

Material Assessment

Evaluation of the material’s baseline viability, activity, and stability profile to determine key sensitivities and establish a starting point for formulation development.

Formulation Design

Development of proprietary stabilization formulations tailored to the material’s sensitivity profile, performance requirements, and intended product format.

03

Protocol Optimization

Refinement of drying protocols to support protective vitrification while preserving viability, activity, and performance in the final dry state.

04

05

Scale-Up Validation

Evaluate optimized VitriStableâ„¢ formulations and protocols in larger-scale or partner-relevant environments to confirm reproducibility, process compatibility, and commercial readiness.

Implementation Pathway

Translate validated VitriStableâ„¢ formulations and protocols into a partner-ready pathway for integration, licensing, and commercialization.

The VitriStableâ„¢ Advantage

Stabilization Comparison

A differentiated technology versus conventional drying methods for sensitive biological materials.

Conventional Freeze-Drying

Stability

Often requires cold chain

SURVIVAL / ACTIVITY

Variable retention

process stress

Freezing + dehydration

Throughput

Slow: 1-5 day cycles

product enablement

Stability-limited

PROPRIETARY TECHNOLOGY

VitriStableâ„¢ Platform

Stability

Target: 2+ years at 25°CAmbient-stable formats

SURVIVAL / ACTIVITY

High-retention design

process stress

Low-temp vaporization

Throughput

Rapid: 1-5 hours

product enablement

Format-ready stable powder

Conventional Spray Drying

Stability

Material-dependent

SURVIVAL / ACTIVITY

Often compromised

Process stress

Heat + atomization

throughput

Fast: minutes

product enablement

Heat-limited

*Results and targets vary by material, formulation, and application. Development may include elevated-temp testing at 37–40°C under accelerated conditions.

bottom of page